Faculty Management System

Academic Information

· Madhyamik from W.B.B.S.E in 2004 with subjects Bengali, English, Physical Science, Life Science, Mathematics, History, Geography, and Additional Mathematics; Division: First (89.5%).

· Higher Secondary from W.B.C.H.S.E in 2006 with subjects Mathematics, Chemistry, Physics, and Biology; Division: First (74%).

· B.Sc. from University of Calcutta in 2009 with subjects Microbiology, Chemistry, Zoology, Bengali, English, and Environmental Science; Specialization: Microbiology (Hons); Division: First (63.9%).

· M.Sc. from University of Calcutta in 2011 with subject Genetics; Specialization: Genetics; Division: First (79.5%).

· NET (CSIR-UGC) in Life Science, qualified in 2010.

· GATE conducted by Indian Institute of Technology in 2011 in Life Science.

· Ph.D. from University of Calcutta in 2019 in Neuroscience; Specialization: Neurogenetics.

Research Areas

neuroscience Genetics cell bilogy

Research Interests

My research interests focus on integrating genetics, transcriptomics, cognitive science, and clinical data to understand neurological disorders such as Parkinson's disease and Stroke. I aim to investigate how gene expression and RNA regulatory mechanisms influence neurodegeneration, cognitive decline, and recovery. By combining RNA-seq data, genetic variation, and clinical cognitive assessments, I seek to identify biomarkers and predictive models of disease progression. My goal is to apply bioinformatics and multi-modal data integration approaches to support precision medicine strategies and improve diagnosis, prognosis, and therapeutic outcomes in neurological disorders.

Courses Taught

biology, molecular biology, microbiology, taxonomy, biochemistry, genetics

Positions Held

JRF at S.N. Pradhan Centre for Neuroscience, University of Calcutta from 01.09.2011 to 31.08.2013.
SRF at S.N. Pradhan Centre for Neuroscience, University of Calcutta from 01.09.2013 to 31.08.2016.
URF at S.N. Pradhan Centre for Neuroscience, University of Calcutta from 05.07.2017 to 30.06.2018.
DST-CSRI, PDF at Department of Biochemistry, University of Calcutta from 01.05.2019 to 30.11.2021.
DST-CSRI, PDF at National Neurosciences Centre Calcutta, Kolkata from 01.04.2022 to 31.03.2024.
DST WISE-PDF at National Neurosciences Centre Calcutta, Kolkata May,2025- terminatedon Jan,2026 for job
Guest Lecturer at S.N. Pradhan Centre for Neuroscience, University of Calcutta from May 2021 to January 2026.

Publications

Sadhukhan D, et al. Transcriptional alteration in TRKβ-SHC isoform as neuroprotective factor for post-stroke memory outcome: regulatory role of genetic polymorphism and DNA methylation. BBRC, Submitted (2025).

Sadhukhan D, et al. Genetic Variants and Alteration in Transcription Factor 7-Like 2 (TCF7L2) mRNA level in Ischemic Stroke Patients: An Indian Scenario. Biochemical Genetics, 2025. DOI: 10.1007/s10528-025-11237-6.

Sadhukhan D, et al. Primary Dystonia and Hypoceruloplasminemia Caused by Digenic Mutations in GNAO1 and CP Gene from Eastern India: A Case Report. International Journal of Clinical Studies & Medical Case Reports, Vol. 50, 2025.

Sadhukhan D, et al. Clinical implication of time of stroke among post-stroke survivors from eastern India: A circadian perspective. Neuromolecular Medicine, Vol. 26, 2024.

Sadhukhan D, et al. Arg4810Lys Mutation in RNF213 among Eastern Indian Non-MMD Ischemic Stroke Patients: A Genotype-Phenotype Correlation. Neurological Sciences, Vol. 45, 2024.

Sadhukhan D, et al. Genetic Variations and Altered Blood mRNA Level of Circadian Genes and BDNF as Risk Factors of Post-Stroke Cognitive Impairment among Eastern Indians. Neuromolecular Medicine, Vol. 25, 2023.

Sadhukhan D, et al. Evaluation of Apolipoprotein e4 allele as susceptible factor for neurodegenerative diseases among Eastern Indians. Austin Alzheimer’s and Parkinson’s Disease, Vol. 6, 2023.

Sadhukhan D, et al. An Indian Young-onset Dementia with Parkinsonism with Double Heterozygous Mutations in ABCA7 and PRKN Identified through Whole-Exome Sequencing. Alzheimer Disease & Associated Disorders, Vol. 37, 2023.

Sadhukhan D, et al. Genetic Polymorphisms in DRD4 and Risk for Parkinson's Disease Among Eastern Indians. Neurology India, Vol. 70, 2022.

Biswas A, Sadhukhan D, et al. Identification of GBA mutations among neurodegenerative disease patients from eastern India. Neuroscience Letters, Vol. 751, 2021.

Sadhukhan D, et al. The Role of the LRRK2 variant p.Gly2019Ser in Indian Parkinsonism patients. Indian Journal of Medical Research, Vol. 151, 2020.

Sadhukhan D, et al. Evaluation of FGF20 variants for susceptibility to Parkinson's disease in Eastern Indians. Neuroscience Letters, Vol. 675, 2018.