Faculty Directory
Debasmita Bhattacharya
Academic Information
PhD, York University, Canada, 2020
Research Areas
Research Interests
My research area focusses on investigation of the cellular intrinsic mechanisms such as autophagy, mitochondrial biology as key regulators of cellular homeostasis, stress adaptation, and disease progression. My work encompasses deciphering therapeutic strategies to attenuate disease progession and improve health. Parallaly, my work also extends to microbiology, especially the biology of biofilms and their impact on host–pathogen interactions, antimicrobial resistance, and chronic infections. I am particularly interested in exploring how microbial biofilms influence cellular stress responses, immune modulation, and tissue repair processes. Overall, my interest seeks to bridge the cellular biology with microbiology to formulate strategies for mitigating tissue damage and enhance cellular health.
Courses Taught
Biology for Engineers, Design Thinking and Innovation, Sustainability, Climate Action and Environmental Sciences
Positions Held
Professor, Institute of Engineering & Management, Kolkata, India
Publications
Journal Publications:
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Microbial-mediated biopolymers (exopolysaccharide) in food packaging: A current time approach in food safety. ACS Food Science & Technology.
Mazumder, S., Bhattacharya, D., Lahiri, D., Moovendhan, M., Sarkar, T., & Nag, M. (2025). Harnessing the nutritional profile and health benefits of millets: A solution to global food security problems. Critical Reviews in Food Science and Nutrition, 65(28), 5550–5571.
Chandra, S., Lahiri, D., Nag, M., Bhattacharya, D., Pandit, C., Pandit, S., et al. (2025). A review on microbial-biofilm mediated mechanisms in marine microplastics degradation. Antonie van Leeuwenhoek, 118(10), 152.
Mazumder, S., Bhattacharya, D., Lahiri, D., Mitra, D., & Nag, M. (2025). Investigation of antioxidant, antimicrobial potential, soil nutriology, and molecular docking study of bioactive compounds of Eleusine coracana (Finger Millet), Pennisetum sp. Biotechnology and Applied Biochemistry.
Chakraborty, S., Chandra, S., Pandit, S., Raj, S., Gill, H. S., Sharma, K., ... & Bhattacharya, D. (2025). Harnessing the power: The role of dissimilatory metal-reducing bacteria in microbial fuel cells. Archives of Microbiology, 207(8), 176.
Majumder, D., Lahiri, D., Nag, M., Bhattacharya, D., Roy, R., Paul, T., & Pandit, S. (2025). Genetically modified lipases as biocatalysts for diacylglycerol production in the food industry: A critical review. Archives of Microbiology, 207(7), 166.
Bhattacharya, R., Chakraborty, A., Samanta, A., Bhattacharya, D., Nag, M., et al. (2025). Antibiofilm activity of green-synthesised ZnO quantum dots by Tinospora cordifolia against modeled biofilm forming organisms. The Microbe, 100427.
Rohilla, Y., Pai, A., Pandit, S., Priya, K., Ranjan, N., Sharma, K., Verma, R., Nag, M., ... & Bhattacharya, D. (2025). A concise review on microbial degradation of pesticides and organohalogen compounds: Recent advances and current challenges. Vegetos, 1–17.
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Rhizobacteria and arbuscular mycorrhizal fungi (AMF) community in growth management and mitigating stress in millets: A plant-soil microbe symbiotic relationship. Current Microbiology, 82(6), 242.
Sil, M., Dey, A., Ghosh, R., Goswami, A., Dalui, S., Chatterjee, I., Bhattacharya, D., et al. (2025). Emerging areas of application of Nano ZnO in combating brain disorders. Current Pharmacology Reports, 11(1), 36.
Gupta, A., Bhattacharya, D., Elayaperumal, S., Sivamani, Y., Lahiri, D., & Nag, M. (2025). Biofilms: A cause for the development of cancer—A review. The Microbe, 100236.
Elayaperumal, S., Sivamani, Y., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Eco-friendly biosurfactant solutions for petroleum hydrocarbon cleanup in aquatic ecosystems. Sustainable Chemistry for the Environment, 100207.
Mukherjee, D., Sil, M., Goswami, A., Bhattacharya, D., Nag, M., Lahiri, D., et al. (2025). Synthesis, modification and antimicrobial potential of biochar and its modifications against water-borne pathogens: A review. Results in Surfaces and Interfaces, 100438.
Sengupta, A., Bhattacharya, D., Lahiri, D., Nag, M., Dey, A., & Ray, S. (2025). Gold and silver nanoparticles as potent quorum quenchers: A critical review. BioNanoScience, 15(1), 73.
Mazumder, S., Bhattacharya, D., Lahiri, D., Moovendhan, M., Sarkar, T., & Nag, M. (2024). Harnessing the nutritional profile and health benefits of millets: a solution to global food security problems. Critical reviews in food science and nutrition, 1–22. Advance online publication. https://doi.org/10.1080/10408398.2024.2417801.
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2024). Milletomics: a metabolomics centered integrated omics approach toward genetic progression. Functional & integrative genomics, 24(5), 149. https://doi.org/10.1007/s10142-024-01430-y.
Lahiri, D., Nag, M., Bhattacharya, D., Samanta, A., Roy, D., Ray, R. R., Ghosh, S., & Dutta, B. (2024). Bacteriocin-mediated food coating: a strategic way to prevent food spoiling and food poisoning bacteria. Nutrire, 49(1). https://doi.org/10.1186/s41110-024-00264-9
Mallick, S., Nag, M., Bhattacharya, D., Tandi, A., Chakraborty, B., Rao, A., Dutta, B., & Ray, R. R. (2024). Green-synthesized ZnO nanorods as potential deefeblement agent of Pseudomonas aeruginosa and Staphylococcus aureus biofilm. Biocatalysis and Agricultural Biotechnology, 57, 103091. https://doi.org/10.1016/j.bcab.2024.103091
Nag, M., Bhattacharya, D., Garai, S. et al. Immobilised antimicrobial peptides in downregulation of biofilm. Naunyn-Schmiedeberg's Arch Pharmacol 397, 5559–5569 (2024). https://doi.org/10.1007/s00210-024-03056-0
Mazumder, S., Bhattacharya, D., Lahiri, D. et al. Milletomics: a metabolomics centered integrated omics approach toward genetic progression. Funct Integr Genomics 24, 149 (2024). https://doi.org/10.1007/s10142-024-01430-y
Majumder, D., Dey, A., Ray, S., Bhattacharya, D., Nag, M., & Lahiri, D. (2024). Use of genomics & proteomics in studying lipase producing microorganisms & its application. Food Chemistry Molecular Sciences, 9, 100218. https://doi.org/10.1016/j.fochms.2024.100218
Sil, M., Mukherjee, D., Goswami, A., Nag, M., Lahiri, D., & Bhattacharya, D. (2023). Antibiofilm activity of mesoporous silica nanoparticles against the biofilm associated infections. Naunyn-Schmiedeberg S Archives of Pharmacology, 397(6), 3617–3633. https://doi.org/10.1007/s00210-023-02872-0
Bhattacharya D, Slavin MB, Hood DA. Muscle mitochondrial transplantation can rescue and maintain cellular homeostasis. Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C862-C884. doi: 10.1152/ajpcell.00212.2023.
Bhattacharya, D., Hood, D.A. Chronic contractile activity remediates lysosomal function in a cellular model mimicking lysosomal disease. (Manuscript under preparation)
Triolo, M., Bhattacharya, D, Hood, D.A. (2022) Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice. Aging, 4;14. doi: 10.18632/aging.204365.
Bhattacharya, D., Shah, V., Oresajo, O., & Scimè, A. (2021). p107 mediated mitochondrial function controls muscle stem cell proliferative fates. Nature Communications, 12 (5977). doi.org/10.1038/s41467-021-26176-0.
Bhattacharya, D., & Scimè, A. (2020). Mitochondrial Function in Muscle Stem Cell Fates.
Frontiers in Cell and Developmental Biology, 2020(8), 480. doi: 10.3389/fcell.2020.00480.
Bhattacharya, D., & Scimè, A. (2019). Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer. Frontiers in Endocrinology, 10. doi: 10.3389/fendo.2019.00773.
Bhattacharya, D., Ydfors, M., Hughes, M. C., Norrbom, J., Perry, C. G. R., & Scimè, A. (2017). Decreased transcriptional corepressor p107 is associated with exercise-induced mitochondrial biogenesis in human skeletal muscle. Physiological Reports, 5(5). doi: 10.14814/phy2.13155.
Porras, D. P., Abbaszadeh, M., Bhattacharya, D., D’Souza, N. C., Edjiu, N. R., Perry, C. G. R.,
& Scimè, A. (2017). p107 Determines a Metabolic Checkpoint Required for Adipocyte Lineage Fates. Stem Cells, 35(5), 1378–1391. doi: 10.1002/stem.2576.
Edited Book Publications:
Bhattacharya, D., Das Biswas, S., & Das, P. K (2025). Advancing Science and Innovation in Healthcare Research: Health Horizons. Academic Press. ISBN 978-0443333514.
Lahiri, D., Nag, M., Bhattacharya, D., Pati, S. & Sarkar, T. (2025). Bioactive Ingredients for Healthcare Industry Volume 2: Advances in Therapeutic Applications. Springer Singapore. https://doi.org/10.1007/978-981-96-4379-0.
Lahiri, D., Nag, M., Bhattacharya, D., Pati, S., & Sarkar, T(2025). Bioactive Ingredients for Healthcare Industry Volume 1: Extraction Strategies, Stability and Medicinal Properties. Springer Nature Singapore. https://doi.org/10.1007/978-981-96-3663-1
Sarkar, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Biofilm Applications to Revolutionize Food Technology. Springer, Cham. https://doi.org/10.1007/978-3-031-85205-3
Lahiri, D., Nag, M., Bhattacharya, D., & Ray, R. R. (2025). Biofilm associated livestock diseases and their management. https://doi.org/10.1007/978-981-96-1885-9.
Book Chapter Publications:
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Harnessing the power of exopolysaccharides for improved gut health. In Extracellular Polysaccharides (pp. 201–217). Springer.
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). EPS in confectionery and snacks: Investigating texture enhancement and shelf-life extension. In Extracellular Polysaccharides (pp. 153–174). Springer.
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Extraction techniques: Past, present, and future. In Extracellular Polysaccharides (pp. 37–56). Springer.
Lahiri, D., Nag, M., Bhattacharya, D., & Ray, R. R. (2025). Biofilm associated livestock diseases and their management. Springer.
Lahiri, D., Nag, M., Bhattacharya, D., Pati, S., & Sarkar, T. (2025). Bioactive ingredients for healthcare industry, Volume 1: Extraction strategies, stability and medicinal properties. Springer Nature.
Lahiri, D., Nag, M., Bhattacharya, D., Pati, S., & Sarkar, T. (2025). Bioactive ingredients for healthcare industry, Volume 2: Advances in therapeutic applications. Springer Nature.
Sarkar, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Biofilm applications to revolutionize food technology. Springer.
Mazumder, S., Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Brewing wonders: Biofilm in beverages. In Biofilm Applications to Revolutionize Food Technology (pp. 275–292). Springer.
Lahiri, D., Mazumder, S., Bhattacharya, D., & Nag, M. (2025). Introduction to modern technological advancement for supervising human health. In Advancing Science and Innovation in Healthcare Research (pp. 1–38). Academic Press.
Bhattacharya, D., Lahiri, D., & Nag, M. (2025). Role of mitochondria in sustaining cellular homeostasis in health and diseases. In Advancing Science and Innovation in Healthcare Research (pp. 125–152). Academic Press.
Mukherjee, D., Chatterjee, N., Lahiri, D., Nag, M., Bhattacharya, D., & Ray, R. R. (2025). Development and utilization of pharmaceutical molecules derived from microalgal biomass. In Plant Specialized Metabolites: Phytochemistry, Ecology and Biotechnology (pp. 1–23). Springer.
Pandit, S., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Pathways and transport mechanism of various metabolites. In Introduction to Metabolic Engineering and Application (pp. 159–171). Springer.
Ramakrishnan, P., Sundaram, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Genetic engineering and modulation of metabolic pathways. In Introduction to Metabolic Engineering and Application (pp. 295–330). Springer.
Upadhyay, A., Mitra, K., Nag, M., Lahiri, D., Bhattacharya, D., & Ghosh, S. (2025). Metabolic control in prokaryotes. In Introduction to Metabolic Engineering and Application (pp. 81–104). Springer.
Mazumder, S., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Models of enzymatic reactions. In Introduction to Metabolic Engineering and Application (pp. 121–157). Springer.
Kumari, R., Nag, M., Lahiri, D., Bhattacharya, D., Ghosh, S., Roy, R., & Paul, T. (2025). Thermodynamics and metabolic flux analysis. In Introduction to Metabolic Engineering and Application (pp. 247–280). Springer.
Ramakrishnan, P., Sundaram, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2025). Metabolic control in eukaryotes. In Introduction to Metabolic Engineering and Application (pp. 31–79). Springer.
Kumari, R., Roy, R., Paul, T., Dey, P., Nag, M., Lahiri, D., & Bhattacharya, D. (2025). Application of MATLAB in metabolic engineering. In Introduction to Metabolic Engineering and Application (pp. 223–246). Springer.
Chakraborty, A., Nag, M., Lahiri, D., & Bhattacharya, D. (2025). Instrumentation techniques in metabolite detection. In Introduction to Metabolic Engineering and Application (pp. 173–189). Springer.
Nag, M., Chatterjee, D., Paul, S., Guha, A., Bhattacharya, D., & Lahiri, D. (2024). Systems Biology Approach in Understanding Mitochondrial Disease. In Systems Biology Approaches: Prevention, Diagnosis, and Understanding Mechanisms of Complex Diseases (pp. 173–193). https://doi.org/10.1007/978-981-99-9462-5_8
Dutta, B., Lahiri, D., Nag, M., Sarkar, N., Ray, R. R., & Bhattacharya, D. (2024). Systems Biology Approaches for Cancer Biology. In Systems Biology Approaches: Prevention, Diagnosis, and Understanding Mechanisms of Complex Diseases (pp. 537–559). https://doi.org/10.1007/978-981-99-9462-5_21
Ghosh, S., Lahiri, D., Nag, M., Ray, R. R., & Bhattacharya, D. (2024). Systems Biology and Hospital-Associated Infections. In Systems Biology Approaches: Prevention, Diagnosis, and Understanding Mechanisms of Complex Diseases (pp. 145–172). https://doi.org/10.1007/978-981-99-9462-5_7
Das, S., Nag, M., Lahiri, D., Bhattacharya, D., & Ray, R. R. (2023). Small molecule associated inhibition of metabolic pathways in biofilm. In CRC Press eBooks (pp. 206–220). https://doi.org/10.1201/9781003281238-12
Dutta, B., Basu, D., Ray, R. R., Sarkar, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2023a). CRISPR/Cas Therapeutics in the Inhibition of Biofilm. In CRC Press eBooks (pp. 190–205). https://doi.org/10.1201/9781003281238-11
Dutta, B., Basu, D., Ray, R. R., Sarkar, T., Lahiri, D., Nag, M., & Bhattacharya, D. (2023b). CRISPR/Cas Therapeutics in the Inhibition of Biofilm. In CRC Press eBooks (pp. 190–205). https://doi.org/10.1201/9781003281238-11
Dutta, B., Lahiri, D., Sarkar, T., Nag, M., Bhattacharya, D., & Ray, R. R. (2023). Case studies: application of lantibiotics as novel drugs. In Elsevier eBooks (pp. 277–299). https://doi.org/10.1016/b978-0-323-99141-4.00011-4
Mukherjee, D., Das, S., Garai, S., Lahiri, D., Nag, M., & Bhattacharya, D. (2023). Bacteriophage Associated Inhibition of Biofilm. In CRC Press eBooks (pp. 221–235). https://doi.org/10.1201/9781003281238-13
Roy, D., Nag, M., Bhattacharya, D., & Lahiri, D. (2023). Microbiologically Synthesized Nanoparticles in Inhibition of Quorum Sensing. In CRC Press eBooks (pp. 102–138). https://doi.org/10.1201/9781003300557-6