Faculty Directory
Dr.Amit Vij
Academic Information
Ph.D
Research Areas
Research Interests
My research interests focus on elucidating the molecular mechanisms by which Leishmania regulates its intracellular environment to survive and proliferate within host macrophages. I am particularly interested in understanding parasite-driven modulation of host signaling pathways, intracellular stress responses, and metabolic adaptations that enable persistence in the hostile phagolysosomal milieu. Insights from this work aim to identify novel molecular targets and pathways for therapeutic intervention against leishmaniasis.
In parallel, I am engaged in the development of lateral flow–based diagnostic assays for the rapid and cost-effective detection of clinically relevant parameters. This includes translating molecular and biochemical insights into point-of-care diagnostic platforms that can improve early disease detection, monitoring, and clinical decision-making, especially in resource-limited settings.
Courses Taught
biochemistry,biology for engineers
Positions Held
Associate Professor
Publications
1) Vij A, Biswas A, Bhattacharya A, Das PK. A Soluble Phosphodiesterase in Leishmania donovaninegatively regulates cAMP signaling by inhibiting protein kinase A through a two way process involving catalytic as well as non-catalytic sites. Int J BIOCHEM Cell Biol 2014; 57: 197-206.
2) Biswas A, Bhattacharya A, Vij A Role of acidocalcisomal pyrophosphatase in the cAMP homeostasis for the infectivity of Leishmania parasites. INT J BIOCHEM CELL Biol 2017; 86:1-13.
3.) Saha A, Bhattacharya.A, Vij A, Das PK Biswas A and Bhattacharya A. Evaluation of modulators of cAMP-response in terms of their impact on cell cycle and mitochondrial activity of Leishmaniadonovani. Front .Pharmacol 11:782.2020.